API¶
Preprocessing¶
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Find background peaks based on GC bias and number of reads per peak |
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Add the DNA sequence of each peak to data object. |
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Compute GC bias for each peak. |
Motif match¶
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Perform motif matching to predict binding sites using MOODS. |
Genome¶
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Download genome |
Compute deviation¶
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Compute raw and bias-corrected deviations. |
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Compute expetation accessibility per peak and per cell by assuming identical read probability per peak for each cell with a sequencing depth matched to that cell observed sequencing depth |